First of all, can you tell us more about yourself? Where are you from, what is your university background?

My name is Zineb BOUARGANE, and I am originally from Marrakech, Morocco. I am a neuroscience doctoral student at Cadi Ayyad University in Marrakech. My academic background is in biology, and I’ve specialized progressively in neuropharmacology and neuroanatomy through coursework and hands-on research. Throughout my academic journey, I’ve been particularly interested in understanding the neurobiological basis of autism spectrum disorder (ASD). I’ve worked on several related projects, including investigating oxidative stress and neurochemical alterations in animal models. I’ve also had the opportunity to supervise and teach students in neuro-related topics, which has helped strengthen both my academic and pedagogical skills.

Why did you choose this career path? What is your interest about science?

I chose this career path because I’ve always been fascinated by the brain and its link to behavior and mental health. My passion for neuroscience deepened especially after completing my Master’s in neuroscience through the EMN program at Cadi Ayyad University, which involved many of the same professors and research groups as PsyCoMed. This experience solidified my research interest and motivated me to pursue a PhD to contribute to advancing knowledge and therapeutic strategies in neurodevelopmental disorders, particularly in under-researched regions.

Can you tell us more about your mobility? Where did you go, for how long? On what kind of research were you working on? Who did you work with?

During my mobility, I spent 12 months in Spain as part of a research secondment. I was hosted by Unitat Predepartamental de Medicina, Facultat de Ciències de la Salut, Universitat Jaume I, where I worked closely with a research group specializing in neuropharmacology and behavioral neuroscience. I worked on two complementary research projects. One was a side project focused on the potential neurotoxic effects of microplastics, exploring how environmental pollutants may impact the developing nervous system. At the same time, I continued my doctoral research, which investigates the role of Selenoprotein T in the valproic acid (VPA)-induced mouse model of ASD. This project aims to understand the molecular and behavioral alterations associated with prenatal VPA exposure and how Selenoprotein T may contribute to neuroprotection. The experience allowed me to collaborate with an amazing international research team, including Prof. Francisco E. Olucha Bordonau, Prof. Esther Castillo Gomez, Prof. Isis Gil Miravet, Monica, Aroa, and Mohamed, expanding my methodological skills and exploring cross-disciplinary questions at the interface of environmental and neurodevelopmental neuroscience. I would like to sincerely thank everyone for their invaluable support throughout my secondment and for the enjoyable moments we shared, both in the animal facility and in the lab and outside of work. These experiences have made my time in Spain truly memorable.

Same question, but for people who don’t understand a thing about neuroscience (#PsyCoMedfordummies)

During my mobility in Spain, I worked on two projects. The first looked at how tiny plastic particles, called microplastics, might affect the brain and overall health. The second was related to my main research, where I study a protein called Selenoprotein T in a model of autism caused by a medication called valproic acid. Basically, I try to understand what happens in the brain during early development when things go wrong, and whether this protein could help protect it. This experience helped me learn new techniques and work with researchers from different backgrounds, which was both exciting and enriching.

What will your research bring to people and to society in general?

My research aims to improve our understanding of how early brain development can be disrupted in conditions like ASD and to explore new ways to protect the brain using molecules like Selenoprotein T. By identifying potential protective mechanisms or therapeutic targets, this work could contribute to developing better strategies for early intervention or treatment. More broadly, it raises awareness about the impact of environmental and chemical exposures during pregnancy, helping both scientists and society better understand how to promote brain health from the very beginning of life.

How do you feel being part of a MSCA Staff Exchange project? What are the benefits of such mobility? What are the results of your secondment?

Being part of the MSCA Staff Exchange project has been a fantastic experience. It allowed me to collaborate with researchers from different backgrounds, which broadened my perspective and helped me refine my scientific skills. The benefits of this mobility include gaining exposure to new research methodologies, strengthening my professional network, and learning how to approach complex interdisciplinary problems. During my secondment, I contributed to the microplastics research, which is now part of the papers I’m writing alongside my thesis. The exchange also allowed me to continue my work on Selenoprotein T in the VPA-induced ASD model, with valuable input from international colleagues. Overall, the mobility has been instrumental in advancing both my thesis and my broader research.

Do you already have future projects you want to share with us?

Yes, I’m already considering my future projects. One of my goals is to continue my research on Selenoprotein T in neurodevelopmental disorders and explore its potential as a therapeutic target for ASD. I’m also planning to extend my work on microplastics and their effects on brain health, with a focus on neurotoxicity. In terms of my next steps, I’m considering applying for a postdoctoral position to further develop these projects and collaborate with international research teams. I’m also open to the possibility of another secondment, which would allow me to broaden my experience and continue building on the skills and networks I’ve developed so far.

Do you have a recommendation/an advice for future potential MSCA fellows?

My advice for future MSCA fellows would be to fully embrace the opportunity for collaboration and learning across different disciplines. The MSCA Staff Exchange program is a chance to expand your skills and knowledge while working with experts from various backgrounds, so take full advantage of this unique exposure. Also, take every opportunity to present your work—like I did at the SONA Congress in Marrakech last month—because sharing your research not only builds confidence but also fosters valuable feedback and networking. Lastly, be open to stepping out of your comfort zone; mobility can be challenging, but it offers incredible opportunities for personal and professional growth.